ncRNA name | HOTAIR |
ncRNA Category | lncRNA |
ID | 100124700 |
Ensembl | ENSG00000228630 |
Synonyms | HOXC-AS4, HOXC11-AS1, NCRNA00072 |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples and adjacent noncancerous tissues; RB cell lines Y79, HXO-Rb44, SO-Rb50 and WERI-RB1 |
Methods | microarray, qRT-PCR, transfection, luciferase reporter assay, colony assay, CCK‐8 assay, apoptosis assay, Western blot |
Expression pattern | up-regulated |
Functional description | The role of lncRNA HOTAIR/miR-613/c-met signalling axis in modulating retinoblastoma cells' viability, apoptosis and expressions of EMT-specific proteins might provide evidences for developing appropriate diagnostic and treatment strategies for retinoblastoma. |
PubMed ID | 30030888 |
Year | 2018 |
Title | LncRNA HOTAIR/miR-613/c-met axis modulated epithelial-mesenchymal transition of retinoblastoma cells. |
Drug-related ncRNA | NO |
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